Artificial intelligence is an emerging field that is generating increasing interest in higher education sectors in many countries, including Mali. The integration of artificial intelligence in higher education can offer several benefits. For example, AI can be used to analyze large amounts of educational data, enabling teachers and decision-makers to make more informed decisions to improve education systems and curricula. AI can also be employed to develop adaptive learning tools that adjust to the needs and learning pace of each student. These tools can provide personalized learning experiences by offering study recommendations, additional exercises, and instant feedback. Moreover, artificial intelligence can be utilized in academic research in Mali. Researchers can leverage machine learning techniques and data analysis to process complex datasets and extract relevant insights. This can contribute to advancing knowledge in fields such as health, agriculture, economics, and other disciplines. However, it is important to note that the integration of AI in higher education also raises challenges and ethical questions. For instance, it is necessary to ensure the protection of student data and to guarantee that decisions made by AI systems are transparent and fair. The evolution of AI in education in Mali could help address specific challenges in the country’s education system while opening new perspectives to improve the quality and accessibility of higher education. Thus, the integration of AI in education in Mali presents significant advantages, but challenges remain, particularly regarding resources and training. The article emphasizes the need for a strategic approach to maximize the impact of AI on human capital (education system) and the socio-economic development of the country.