The place of the in vivo vibration methods in the investigation of the mechanical characteristics of the tibial bone becomes a key to the development of the clinical diagnostics and research. Bone biomechanics, which is a combination of mechanical knowledge and biological knowledge, has been used majorly in the analysis of skeletal functionalities as well as the safety among the skeletal structures particularly the tibia which is a weight-bearing bone that is significant in the movement of humans. Conventional techniques, like X-rays and MRIs, will give the structural information, however these do not render the real life mechanical dynamics of bone. Vibration means The use of vibration in vivo What is the measurement of response to vibration of low frequencies to bone; these vibration methods have proven to be non-invasive accurate ways to measure bone health; particularly, bone density, stiffness, and elasticity. This review examines the use of the vibration measurement techniques on the tibia including osteoporosis, fractures and the post operation conditions. Through vibrational responses, these methods yield meaningful information with respect to the strength of the bone as far as injury prevention and the selection of rehabilitation measures are concerned. Due to emerging technologies like wearable sensors and computational modeling, the methods are also expected to improve the real-time measurements and accuracy to assist in clinically accurate decision-making in orthopedics.