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QUALITY CONTROL STUDIES IN THE TURKEY MARKET ON SOFT GELATIN CAPSULES CONTAINING CHIA (SALVIA HISPANICA L.) SEEDS OIL


Author: Ebru Derici Eker*, Mohammed Yahia Asaad
Published Date: 2024-09-21
Keywords: Salvia hispanica L. (chia seeds oil), omega-3, soft gelatin capsule, quality control.
Abstract:
Chia seed, which has its origins in prehistoric times, is a food that has become popular as a superfood with its high content of oil, protein and dietary fiber. Chia seeds contain 17-24% protein, 18-30% fiber and 25-40% fat. 80% of the oil content of the seed consists of α-linolenic acid (omega-3) and linoleic acid (omega-6). Since the preparations available in the market in our country are put on the market with the permission of the Ministry of Agriculture, they do not need to pass in vitro and in vivo efficacy, safety and quality control tests like the human drugs licensed by the Ministry of Health. In our study, it is aimed to evaluate the quality control of chia seed oils and soft capsule formulations with different formulations marketed by different companies in the Turkish market. Determination of organoleptic properties, weight deviation, disintegration test, dissolution test, DPPH antioxidant capacity measurement and phenolic substance determination analyzes were performed on soft gelatin capsules containing chia seed oil and oils. According to the data obtained, the capsules are suitable in terms of organoleptic properties. The mean weight deviation of soft gelatin capsules was 0.7283±0.024g for sample A and 1.2947±0.015g for sample B. According to the results obtained from the disintegration test, the capsules dispersed between 5 minutes 14 seconds and 6 minutes 32 seconds in the artificial stomach medium, between 5 minutes 14 seconds and 6 minutes 32 seconds in the artificial gut medium, and between 16 minutes 2 seconds and 18 minutes 30 seconds in pure water. We think that its use as an herbal supplement would be appropriate due to the results in accordance with the literature in quality control tests on soft gelatin capsules and oils containing chia seed oil.

Journal: ISAR Journal of Medical and Pharmaceutical Sciences
ISSN(Online): 2584-0150
Publisher: ISAR Publisher
Frequency: Monthly
Language: English

QUALITY CONTROL STUDIES IN THE TURKEY MARKET ON SOFT GELATIN CAPSULES CONTAINING CHIA (SALVIA HISPANICA L.) SEEDS OIL
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