International Scientific and Academic Research Publisher
INVESTIGATION OF ANTIMICROBIAL PROPERTIES OF SOME SCHIFF BASES
Author: Bekir Sıtkı Çevrimli, Sinan Mithat Muhammet, Şükrü Kalaycı*
Published Date: 2023-12-05
Keywords: Schiff base; azo-pyrazole; antimicrobial activity; well diffusion method.
Abstract:
Schiff bases; 3-(2-hydroxy-1-salicylaldimine)-5-amino-4-(3-nitro-phenylazo)-1Hpyrazole (3N-sal), 3-(2-hydroxy-1-salicylaldimine)-5-amino-4-(3-bromo-phenylazo)-1Hpyrazole (3Br-sal), 3-(2-hydroxy-1-naphtaldimine)-5-amino-4-(3-nitro-phenylazo)-1Hpyrazole (3N-naf) and 3-(2-hydroxy-1-naphtaldimine)-5-amino-4-(3-bromo-phenylazo)-1Hpyrazole (3Br-naf) were synthesized by the condensation of some azo-pyrazole diamines with aromatic aldehydes at the same rate. The chemical structures of these compounds were elucidated using molecular spectroscopy methods. The antimicrobial proporties of schiff bases were investigated against bacteria.