This study was designed to investigate ICT acceptance and adoption as predictors of information use environment among secondary school students in newly upgraded state universities Southwest, Nigeria. Survey research design was employed for the study, the population size consisted of 337 students of Senior Secondary School One (SSS I) using total enumeration sampling technique. Questionnaire was the instrument used for data collection; seven research questions and three null hypotheses were formulated for this study. Output format of SPSS based on simple frequency count, percentage distribution, mean, standard deviation, Pearson’s Product Moment Correlation (PPMC) and multiple regression were used for data analysis. The findings of this study revealed that there was a significant relationship between ICT acceptance and Information Use Environment as well as a significant relationship between ICT adoption and Information Use Environment. Information sources and information services mostly used are electronic dictionaries, electronic books, educational softwares and internet, mobile phone and television while mobile phone, internet, television and social media respectively are the mostly used ICT resources for information among secondary school students in newly upgraded state universities in Southwest, Nigeria. The location of their information use environment are their homes, school library or school resource centre as well as the parents’ offices for academic and entertainment purposes. The major identified problems in the use of information environment are: instability of network services, that is, internet connectivity, information overload, ineffective use of technology, unstable power supply. Part of the recommendations made was that that Government should ensure that ICT policy statements are translated into reality; school management should invest in custom-made digital materials with highly relevant content suitable for secondary school students. These will cub the abuse/ misuse of internet.