This study explores the intricate realm of integrating cyber-physical systems (CPS) with wireless communication protocols to enhance the capabilities of Internet of Things (IoT) applications. The research focuses on simulating wireless communication within IoT networks, placing significant emphasis on critical factors such as signal strength, interference, and propagation models. By employing advanced simulation tools like OMNeT++, a comprehensive evaluation is conducted on various communication protocols, including Zigbee and LoRa, with a thorough analysis of their performance metrics. One of the primary objectives is to understand the impact of signal strength and interference on the reliability and efficiency of wireless communication in diverse IoT scenarios. Through meticulous experimentation and simulation, the study aims to uncover insights into how these factors influence the overall performance of IoT systems. Additionally, the research investigates the optimization strategies for wireless communication protocols, particularly in the context of CPS integration, to enhance the functionality and resilience of IoT applications. The findings from this study hold significant implications for the future development and implementation of IoT technologies. By gaining a deeper understanding of CPS integration and wireless communication optimization, practitioners and researchers can design more robust and efficient IoT systems capable of meeting the complex demands of modern applications. This contributes to advancements in IoT technology by addressing key challenges related to communication reliability, signal integrity, and overall system performance. Ultimately, the research paves the way for the evolution of smarter and more interconnected IoT ecosystems that benefit industries, communities, and individuals alike.