While livestock farming plays a major role in food security, livelihoods and rural economies especially in the developing world, environmental, social-economic, cultural and political factors increasingly threaten livestock farming in these areas. This study classifies livestock vulnerability threats and indigenous adaptation strategies to cope with such threats in Babadjou Sub-division. To realize this aim, data was obtained from both secondary and primary sources. Secondary data were obtained from published and unpublished documents consulted from online, libraries of Universities and specialized institutions found in Babadjou. Primary data were gotten through the administration of 398 copies of questionnaire, Focus Group Discussions, personal interviews, direct and indirect field observations. Data were descriptively processed with the help of Excel version 2013, meanwhile content analysis was used for qualitative data. Results were qualitatively and presented in the form of tables, charts, photograph and percentages. The study identified six types of livestock reared in Babadjou Sub-division including cattle, goats, sheep, pigs, guinea pigs and fowls. The study further established that livestock rearing in this community is exposed to several vulnerability threats that span through environmental (water scarcity-38.2% and pastures scarcity-33.6%) market (price volatile-42%, consumers preference-15.6% and price of feed-49.7%), production (theft-32.8% and adequate breeding skills-31.2%) and health (diseases and parasites attacks) threats. As a consequence, livestock farmers have resorted to the practiced of transhumance (30.3%), animal de-ticking, keeping of dogs (28.5%), feeding of animals with salt (38.2%), application of red oil mixed with kerosene on livestock (23.7%), shooting of hawks with rubber gun (25.0%), animal feed mixed with pepper (15.6%) and animal feed mixed with salt (28.7%) as indigenous adaptation strategies to the vulnerability threats of livestock rearing in Babadjou Sub-division. The study concludes that the indigenous strategies play an important role in livestock rering in Babadjou Sub-division and recommends that both conventional and indigenous strategies should be integrated in livestock rearing to enhance livestock sustainbaility.